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id="inside_rnewtil">霉菌污染問題應采取什么方法防控？</h1> <div id="73bdjbx" class="inside_rnewtime">更新時間：2024-08-16 點擊次數(shù)：259次</div> <div id="nj7n5nz" class="inside_rnewcon"><p>霉菌是污染制藥車間的主要微生物之一，在適宜的條件下霉菌可以大量繁殖，車間一旦被霉菌污染，就會對產(chǎn)品質(zhì)量和員工健康構(gòu)成威脅，霉菌治理刻不容緩。獸藥生產(chǎn)公司應當采取一系列有效措施防止霉菌污染，以此降低污染對車間帶來的影響。</p><p><br/></p><p style="text-align: center;"><img class="rich_pages wxw-img js_insertlocalimg" data-backh="386" data-backw="578" data-imgfileid="100000194" data-ratio="0.667" data-s="300,640" data-src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/jpzIw44Ib6nKYvvJ32wQ7icLXMwnsqGlsZxVq0lbS53AWBQG3O7IOXUTmyF1aqp7fPk3TaBDKCNDZZrvXrsrlcg/640?wx_fmt=jpeg&from=appmsg" data-type="jpeg" data-w="1000" data-original-style="width: 100%;height: auto;" data-index="3" src="https://img60.chem17.com/9/20240816/638594044219583829450.jpg" _width="100%" crossorigin="anonymous" alt="霉菌污染問題應采取什么方法防控？" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: bottom; height: auto !important; width: 677px !important; visibility: visible !important;"/></p><p><br/></p><p>一、獸藥生產(chǎn)相關(guān)規(guī)定列舉</p><p><br/></p><p>《獸藥生產(chǎn)質(zhì)量管理規(guī)范（2020年修訂）》第四章廠房與設施第二節(jié) 生產(chǎn)區(qū)對獸藥的生產(chǎn)過程有以下要求：</p><p><br/></p><p style="text-align: center;"><img class="rich_pages wxw-img" data-backh="309" data-backw="550" data-cropselx1="0" data-cropselx2="552" data-cropsely1="0" data-cropsely2="276" data-imgfileid="100000185" data-ratio="0.5625" data-src="https://mmbiz.qpic.cn/sz_mmbiz_png/jpzIw44Ib6nKYvvJ32wQ7icLXMwnsqGlsewotoLb5l5Iq9AhzTpOSGFghEHu3ApC4uycG12bibxU7hfQUs00yukg/640?wx_fmt=png&from=appmsg" data-type="gif" data-w="1040" data-original-style="background-position: center center;background-size: initial;background-repeat: no-repeat;background-attachment: initial;background-origin: initial;border-width: 1px;border-style: solid;border-color: rgb(221, 221, 221);vertical-align: bottom;background-clip: initial;width: 100%;height: auto;" data-index="4" src="https://img60.chem17.com/9/20240816/638594044220521557555.jpg" _width="100%" crossorigin="anonymous" alt="霉菌污染問題應采取什么方法防控？" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: bottom; height: auto !important; background-position: center center; background-size: initial; background-repeat: no-repeat; background-attachment: initial; background-origin: initial; border-width: 1px; border-style: solid; border-color: rgb(221, 221, 221); background-clip: initial; width: 677px !important; visibility: visible !important;"/><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>二、霉菌污染的原因</p><p><br/></p><p>1. 濕度和溫度：霉菌的生長和繁殖與濕度和溫度密切相關(guān)。在濕度較高、溫度適宜的環(huán)境下，霉菌容易滋生和擴散。生產(chǎn)車間的墻壁、設備、管道等如果存在潮濕問題，就容易成為霉菌的生長場所。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>2.通風不良：通風不良會導致車間內(nèi)空氣濕度和溫度分布不均，增加霉菌生長的風險。此外，通風不良還會使車間內(nèi)的有害氣體和微生物難以排出，進一步惡化生產(chǎn)環(huán)境。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>3.清潔不合格：生產(chǎn)設備、工作臺面、地面等如果清潔不到位，也容易滋生霉菌。同時，清潔過程中使用的清潔劑和消毒劑如果選擇不當或使用方法不正確，導致霉菌產(chǎn)生耐藥性，無法有效殺滅霉菌。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>4.設備和管道問題：生產(chǎn)設備和管道如果存在泄漏、破損或設計不合理等，會導致水分和有機物在設備內(nèi)部或管道中殘存，為霉菌提供生長條件。</p><p><br/></p><p>5.人員因素：人員進出生產(chǎn)車間可能攜帶霉菌孢子，特別是在潮濕或發(fā)霉的環(huán)境中人員走動容易帶動霉菌孢子飄散或附著在人員衣物上。此外，員工的個人衛(wèi)生習慣也會影響車間的霉菌污染情況。</p><p><br/></p><p>三、霉菌污染的危害<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>1.影響產(chǎn)品質(zhì)量：霉菌污染會導致產(chǎn)品變質(zhì)、發(fā)霉或產(chǎn)生異味，嚴重影響產(chǎn)品的質(zhì)量和市場信譽。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>2.危害員工健康：長期暴露在霉菌污染的環(huán)境中，員工可能出現(xiàn)呼吸道疾病、過敏反應等健康問題。</p><p><br/></p><p>3.增加生產(chǎn)成本：為了控制霉菌污染，企業(yè)需要投入更多的資源和資金進行清潔、消毒和維修等工作，從而增加生產(chǎn)成本。</p><p><br/></p><p>四、霉菌污染的防控措施<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>1.控制濕度和溫度：通過安裝除濕設備、調(diào)節(jié)空調(diào)系統(tǒng)等措施，將車間內(nèi)的濕度和溫度控制在適宜范圍內(nèi)，抑制霉菌的生長和繁殖。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>2.加強通風換氣：定期開啟門窗、安裝通風設備等，保持車間內(nèi)空氣流通，減少霉菌生長的機會。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>3.定期清潔和消毒：制定詳細的清潔和消毒計劃，<span style="text-wrap: wrap;">選擇合適的清潔劑和消毒劑</span>對生產(chǎn)設備、工作臺面、地面等進行定期清潔和消毒。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>4.檢查和維護設備和管道：定期檢查生產(chǎn)設備和管道是否存在泄漏、破損等問題，并及時進行維修和更換。確保設備和管道內(nèi)部無水分和有機物殘存，若有及時清理并使用適合的消毒劑進行滅菌。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>5.加強人員培訓和管理：定期對員工進行霉菌污染防控知識的培訓和教育，提高員工的衛(wèi)生意識和防控能力。同時，建立嚴格的出入管理制度和個人衛(wèi)生習慣管理規(guī)范，減少因人員因素導致的霉菌污染風險。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>6.建立監(jiān)測和預警機制：建立定期監(jiān)測和預警機制，對車間內(nèi)的霉菌污染情況進行實時監(jiān)測和評估。一旦發(fā)現(xiàn)霉菌污染問題，立即采取措施進行處理并查明原因，防止問題進一步擴大。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>五、奧克泰士殺孢子劑可有效解決霉菌污染問題<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>殺孢子劑較75%乙醇、新潔爾滅等消毒劑對霉菌的作用效果更顯著。奧克泰士作為一種過氧化氫銀離子復合型消毒劑，能殺滅霉菌等容易產(chǎn)生耐藥性的高抗性微生物，可有效解決生產(chǎn)車間霉菌污染的問題。</p><p><br/></p><p>奧克泰士針對霉菌污染有以下優(yōu)點：</p><p><br/></p><p>1.成分安全：活性物質(zhì)是過氧化氫，一種食品級、環(huán)境友好的物質(zhì)。作用于霉菌時其活性可被銀離子穩(wěn)定并增強，從而大大提高殺菌效果。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>2.廣譜性、高效性：可殺滅包括霉菌在內(nèi)的真菌、各種細菌、病毒等多種容易引起污染的微生物，殺菌效果持續(xù)時間長，殺菌率高達99.999%。</p><p><br/></p><p>3.無毒害：經(jīng)奧克泰士處理后的物體表面中銀離子極其微量不可見，作用過程無毒副產(chǎn)物，且無色無味，不會危害人體健康。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>4.無腐蝕性：不會與其他化學元素發(fā)生化合反應，對設備基本無腐蝕性。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>5.操作方便：可通過噴灑、擦拭、浸泡等對車間設備及環(huán)境進行消殺。<br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p><br/></p><p>綜上所述，生產(chǎn)車間霉菌污染的防控需要綜合考慮多種因素，并采取對應措施進行治理。通過對濕度和溫度加強控制、通風換氣、清潔消毒、設備維護、人員培訓和管理以及使用合適的消毒劑等，可以有效地降低霉菌污染的風險并保障生產(chǎn)環(huán)境的衛(wèi)生和安全。</p><p><br/></p><p style="text-align: center;"><img class="rich_pages wxw-img js_insertlocalimg" data-backh="771" data-backw="578" data-imgfileid="100000193" data-ratio="1.3333333333333333" data-s="300,640" data-src="https://mmbiz.qpic.cn/sz_mmbiz_png/jpzIw44Ib6nKYvvJ32wQ7icLXMwnsqGlsS8VxlZtvwXeQd8PFmrnUNTT9oviaNgkX3Dia712gWOSfnrZzuV5c56Ag/640?wx_fmt=png&from=appmsg" data-type="png" data-w="750" data-original-style="width: 100%;height: auto;" data-index="5" src="https://img60.chem17.com/9/20240816/638594044222239975786.jpg" _width="100%" crossorigin="anonymous" alt="霉菌污染問題應采取什么方法防控？" data-fail="0" style="margin: 0px; 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